So Many Drugs for Schizophrenia

Our next issue includes an article on lumateperone (Caplyta – Intracellular Therapies), a new oral treatment for schizophrenia. Lumateperone is the 13th second-generation drug for this indication, and there are 8 first-generation drugs still out there as well. Why are 21 drugs with more-or-less similar mechanisms of action being marketed for the same disease? One […]

Early Use of Remdesivir (Continued)

Two important communications turned up on my computer recently. First, two letters to the editor of The New England Journal of Medicine commenting on Beigel et al, Remdesivir for the Treatment of Covid-19 — Preliminary Report, published online on May 22 at NEJM.org. Both drew attention to the late introduction of remdesivir in the trial: […]