Vitamin D Supplements

The July 28th issue of The New England Journal of Medicine included results from a large, randomized, placebo-controlled trial of vitamin D supplementation to lower the risk of fractures in middle-aged and older adults who were not selected based on gender, vitamin D deficiency, low bone mass, or osteoporosis. Supplementation with vitamin D3 2000IU/day did not reduce the risk of fractures over a median follow-up of 5.3 years (MS LeBoff et al. N Engl J Med 2022; 387:299).  The article was accompanied by an editorial reminding readers that the results of previous studies had shown that vitamin D supplementation did not prevent cancer, cardiovascular disease, or a host of other conditions and urging providers not to screen patients for vitamin D deficiency and not to recommend use of vitamin D supplements (SR Cummings and C Rosen. N Engl J Med 2022; 387:368).

A 10-year-old page from The Medical Letter reproduced below with 2 updated tables reported a similar recommendation on this subject from the US Preventive Services Task Force (USPSTF). The tables offer some dietary alternatives for patients who are reluctant to stop taking vitamin D.

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